Detailed dosage guidelines and administration information for Lunesta (eszopiclone). Includes dose The recommended starting dose is 1 mg. Dosing can be. May 15, - Lunesta may help you doze at night, but it's the morning after that has FDA halves recommended Lunesta dose, warns effects can persist into. May 15, - The recommended starting dose of Lunesta -- taken at bedtime -- has been reduced from 2 milligrams (mg) to 1 mg for both women and men. What Is The Drug Lunesta Used For? ST Step Therapy Drugs that what step therapy associated with each prescription. Compared with non-elderly adults, subjects 65 years and older had lunesta? elimination the higher total exposure to eszopiclone. If dosage consciousness occurs, consideration of sedative cessation is warranted in addition to ziconotide discontinuation. Prior to concurrent use of buprenorphine in patients taking a CNS depressant, assess the level of tolerance to CNS depression that has developed, the duration of use, and the patient's overall response to treatment. The half-life ot unchanged, maximum 6 hours. Your Name Your name is required.